Zestril Dosing

Zestril Dosing for Congestive Heart Failure

The recommended starting dose of Zestril for people with congestive heart failure is 5 mg, taken once daily. Zestril has been approved as add-on therapy to diuretics and digoxin (such as Digitek® and Lanoxin®) or digitoxin and should, therefore, be monitored carefully when starting treatment.
After two weeks, if you have not reached your treatment goals, your healthcare provider may increase your dosing by 10 mg. The Zestril dose can also be decreased if side effects occur.
If you have both heart failure and kidney disease, your healthcare provider may choose to start you on a lower dose of Zestril, such as 2.5 mg a day.

Zestril Dosage After a Heart Attack

If you have had a heart attack (myocardial infarction) and are stable within 24 hours, Zestril may be used to improve the chances of survival. The recommended starting dose is 5 mg, followed by another 5 mg in 24 hours, and then 10 mg at 48 hours. This Zestril dose of 10 mg may then be continued for six weeks.
If you have kidney disease and are taking Zestril for an acute heart attack, your healthcare provider may choose to proceed with caution.

Zestril Dosing in Children

The recommended starting dose of Zestril for children 6 years of age and older is 0.07 mg/kg once a day (up to 5 mg total).

General Information on Zestril Dosing

Some considerations for people taking Zestril include the following:
  • Your Zestril dosage should be taken by mouth with a glass of water.
  • Zestril may be taken with or without food.  


  • Make sure to take Zestril at the same time each day to maintain even levels of the medication in the blood.
  • For Zestril to work properly, you have to take it as prescribed. Zestril will not work if you take in a way other than how your healthcare provider has recommended.
  • If you do not take your Zestril as scheduled, take your next dose as soon as you remember. If it is almost time for the next scheduled dose, skip the missed one and continue with normal dosing. Do not take a double dose.
  • If you are unsure about anything related to Zestril or Zestril dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking Zestril without first discussing it with your healthcare provider.
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