General considerations for when and how to take the medication include the following:
- It comes in capsule form. It is usually taken by mouth twice a day after meals.
- Triamterene should be taken at the same times each day to maintain an even level in your blood. However, some people do not need to take it every day, especially those who are taking the medication for fluid retention.
- Because the medication increases urination, it is best to take your last dose of the day before 6 p.m. (to avoid needing to get up to use the bathroom throughout the night), unless your healthcare provider instructs you otherwise.
- For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.
The dosage that your healthcare provider recommends will vary, depending on a number of factors, including:
- Other medical conditions you may have
- Other medications you may be taking
- How you respond to triamterene.
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Triamterene Dosing for more information.)
As with any medicine, side effects are possible. However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
A few of the possible side effects of triamterene include:
- Weakness or fatigue
- Dry mouth (see Dyrenium and Dry Mouth)
- Nausea or vomiting
- Kidney stones
- Sensitivity to the sun
- High potassium levels in the blood (hyperkalemia).
(Click Triamterene Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)