Drug Interactions With Triamterene

Several medications may cause drug interactions with triamterene, including angiotensin II receptor blockers, nonsteroidal anti-inflammatory drugs, and ACE inhibitors. These interactions can increase your risk of side effects, such as high blood sugar or high potassium levels, and affect the level of medicines in your blood. If drug interactions with triamterene are a concern, your healthcare provider may adjust your dosages or monitor you more carefully.

Drug Interactions With Triamterene: An Overview

Triamterene (Dyrenium®) can potentially interact with a number of other medicines. Some of the medications that can cause triamterene drug interactions include:
 
  • ACE inhibitors, such as:
 
 
 
  • Angiotensin II receptor blockers (ARBs), such as:
 
 
 
  • Digoxin (Digitek®, Lanoxin®)
 
 
 
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
 
 
  • Potassium-containing products, such as:
 
    • Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
    • Potassium citrate (Urocit-K®, Polycitra-K®)
    • Potassium gluconate
    • Potassium phosphate (Neutra-Phos-K®, K-Phos®)
    • Salt substitutes (used to flavor food)
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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