Monopril Drug Interactions (Cont.)

More Detail About Monopril Interactions

 
Diuretics
When taking Monopril with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Monopril is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dosages of either medicine, start you on a lower dose of Monopril, and/or monitor you more closely.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
If you have kidney disease or kidney failure, taking both NSAIDs and Monopril may add to the damage that your kidneys are already experiencing. Also, NSAIDs may decrease the effects of Monopril on lowering blood pressure. For your particular situation, talk to your healthcare provider about using NSAIDs and Monopril together.
 
Potassium Supplements
If you are taking a potassium supplement and Monopril, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and Monopril together.
 
Potassium-Sparing Diuretics
If you are taking both Monopril and a potassium-sparing diuretic, your body may metabolize the drugs differently than intended and/or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress closely.
 
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both Monopril and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently.
 
Antacids
Taking antacids with Monopril may decrease the absorption of Monopril into the body. If you are taking antacids, they should be taken at least two hours before or after taking Monopril tablets.
 
(Monopril Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;