Drug Interactions With Metoprolol Succinate

Among the drugs that can potentially interact with metoprolol succinate are nonsteroidal anti-inflammatory drugs, calcium channel blockers, and alpha blockers. Drug interactions may cause your body to metabolize the medications differently than intended and increase the level of metoprolol succinate in your body, among other things.

Metoprolol Succinate Interactions: An Overview

Metoprolol succinate (Toprol-XL®) can potentially interact with a number of other medicines. Some of the medications that can lead to metoprolol succinate drug interactions include:
 
 
 
 
 
  • Certain arrhythmia medications, such as:
     
    • Amiodarone (Cordarone®)
    • Disopyramide (Norpace®, Norpace CR®)
    • Lidocaine (Xylocaine®)
    • Propafenone (Rythmol®)
    • Quinidine
    • Sotalol (Betapace®)
 
 
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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