Drug Interactions With Metoprolol Succinate

More Information on Drug Interactions With Metoprolol Succinate

The following sections explain in detail the potentially negative interactions that can occur when metoprolol succinate is combined with any of the drugs listed above.
 
Alpha Blockers
Combining metoprolol succinate with an alpha blocker can increase the risk of dangerously low blood pressure (hypotension). Check with your healthcare provider before combining such medications.
 
Calcium Channel Blockers
Taking metoprolol succinate with certain calcium channel blockers may cause a dangerously low blood pressure and (for verapamil or diltiazem), a slow heart rate (bradycardia). You may need to be monitored closely if you take these medications together. In some cases, metoprolol succinate should not be combined with a calcium channel blocker.
 
Certain Antidepressants
If you are taking metoprolol succinate and certain antidepressants, your body may metabolize metoprolol succinate differently than intended. This can cause an increased level of metoprolol succinate in your body. If you are using these medicines together, your healthcare provider may choose to monitor you more closely and/or adjust your metoprolol tartrate dose.
 
Certain Antipsychotics
If you are taking metoprolol succinate and certain antipsychotics, your body may metabolize metoprolol succinate differently than intended. This can cause an increased level of metoprolol succinate in your body. If you are using these medicines together, your healthcare provider may choose to monitor you more closely and/or adjust your dose of metoprolol tartrate.
 
Certain Arrhythmia Medications
Combining metoprolol succinate with certain arrhythmia medications may cause a dangerously slow heart rate (bradycardia). You may need to be monitored closely if you take these medications together. In some cases, metoprolol succinate should not be taken with an arrhythmia medication.
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