Metolazone (Cont.)

When and How to Take Metolazone

General considerations for when and how to take metolazone include the following:
 
  • The medication comes in tablet form. It is taken by mouth, usually once a day.
     
  • You can take metolazone with or without food.
     
  • Metolazone should be taken at the same time each day to maintain an even level in your blood. However, some people do not need to take the drug every day, especially people taking it for fluid retention.
     
  • Because metolazone increases urination, it is best to take the medication in the morning (to avoid having to get up to use the bathroom throughout the night), unless your healthcare provider instructs you otherwise.
     
  • For the medication to work properly, it must be taken as prescribed. Metolazone will not work if you stop taking it.
     

Who Makes Metolazone?

Metolazone is made by UCB Pharma. Generic metolazone is made by various manufacturers.
 

Strengths of Metolazone

Metolazone tablets are available in the following strengths:
 
  • Metolazone 2.5 mg tablets
  • Metolazone 5 mg tablets
  • Metolazone 10 mg tablets.
     

Generic Metolazone

Currently, both brand-name and generic versions of metolazone are licensed for sale (see Generic Zaroxolyn).

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;