Drug Interactions

Metolazone can potentially interact with a few medicines (see Drug Interactions With Metolazone).

What If I Take an Overdose of Metolazone?

People who take too much metolazone may have overdose symptoms that could include:
  • Low blood pressure (hypotension)
  • Dizziness
  • Drowsiness
  • Fainting
  • Electrolyte imbalance
  • Dehydration
  • Difficulty breathing
  • Lethargy
  • Coma
  • Kidney problems.
If you happen to take an overdose, seek immediate medical attention.
(Click Metolazone Overdose for more information.)

How Should Metolazone Be Stored?

This medication should be stored at room temperature, away from moisture and heat. The tablets should be kept in an airtight container.
Keep this and all medications out of the reach of children.

What Should I Do If I Miss a Dose?

If you do not take your metolazone as scheduled, take your missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose.

How Does It Work?

Metolazone is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amount of salt and water the kidneys remove from the blood. This extra salt and water is then passed out through the urine. By increasing the amount of water removed from the blood, the medication causes a decrease in blood volume. Because of this effect, the drug can lower blood pressure and can also help with water retention.
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Metolazone Drug Information

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