For example, when treating congestive heart failure in adults, the recommended starting digoxin dose is normally 0.25 mg (250 mcg) once daily. It normally takes one to three weeks after you start digoxin treatment for an adequate amount of the drug to accumulate in your body. Your healthcare provider may adjust your dose, no more often than every two weeks, based on how you respond to the medication and your digoxin blood level.
Blood levels between 0.5 and 2 ng per mL are considered normal therapeutic levels. Most people will likely be maintained on a digoxin dosage between 0.125 mg and 0.25 mg to achieve this level. Digoxin toxicity is likely to occur if levels exceed 2 ng per mL.
(Click Digoxin Dosage for more in-depth information. This full-length article provides more specific dosing guidelines for treating adults and children with congestive heart failure or atrial fibrillation. A list of tips on how to take the drug is also included.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
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