Congestive Heart Failure Home > Action of Digoxin

People with congestive heart failure or atrial fibrillation may benefit from digoxin (Lanoxin®). This prescription drug comes in the form of a tablet, an injection, and an oral liquid (elixir).
Digoxin belongs to a class of drugs called cardiac glycosides or digitalis glycosides. Digitalis medications, such as digoxin, are extracted from the digitalis plant, which is more commonly known as foxglove.
Digoxin works by blocking sodium-potassium ATPase, an enzyme in the body that controls the amount of sodium and potassium that enters the cells. By blocking this enzyme, digoxin increases the amount of calcium and potassium inside heart cells. With this action, digoxin helps the heart contract more forcefully with each heartbeat, making it more efficient at pumping blood throughout the body. It also slows down the rate at which the heart beats.
(Click Digoxin for a closer look at the drug's actions on the heart and how it works to make the heart more efficient. This article also lists possible side effects, covers general dosing guidelines, and explains why this drug is not suitable for some people.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.