Congestive Heart Failure Home > Chlorthalidone Side Effects

While most people have no problems with chlorthalidone, side effects are possible. A few of the side effects that have been reported in clinical trials include loss of appetite, nausea, and diarrhea. Side effects of this medicine are usually minor and easily treated. However, some side effects -- including jaundice or signs of an allergic reaction -- should be reported to your healthcare provider.

An Overview of Chlorthalidone Side Effects

As with any medicine, side effects are possible with chlorthalidone (Thalitone®); however, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, possible side effects with chlorthalidone. Your healthcare provider can discuss a more complete list of chlorthalidone side effects with you.)

Reported Chlorthalidone Side Effects

Chlorthalidone has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
Based on these studies, some of the possible side effects of chlorthalidone include:
  • Loss of appetite
  • Stomach irritation
  • Nausea or vomiting
  • Diarrhea or constipation
  • Dizziness
  • Vertigo (a spinning sensation)
  • Abnormal sensations, such as burning or tingling (paresthesias)
  • Headaches
  • Vision changes
  • Sensitivity to the sun
  • Impotence.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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