Congestive Heart Failure Home > Drug Interactions With Captopril

Medicines that may potentially cause drug interactions with captopril include aspirin or other nonsteroidal anti-inflammatory drugs, potassium supplements, and diuretics, among others. These interactions may cause your body to metabolize the medicines differently than intended and lead to decreased effectiveness of the drugs. If drug interactions are a concern, your doctor may monitor you more closely or adjust your dosage.

Interactions With Captopril: An Introduction

Captopril (Capoten®) can potentially interact with a number of other medicines. Some of these drug interactions with captopril can include:


  • Potassium-containing products, such as:
    • Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
    • Potassium citrate (Urocit-K®, Polycitra-K®)
    • Potassium gluconate
    • Potassium phosphate (Neutra-Phos-K®, K-Phos®)
    • Salt substitutes (used to flavor food)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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