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Animal studies on amiloride and pregnancy indicate that the drug may be safe for pregnant women; however, the full risks are not known. Generally, diuretics (including amiloride) are not recommended during pregnancy, except when absolutely necessary. If you are taking amiloride and pregnancy occurs, your healthcare provider will consider the benefits and risks in your particular situation.

Amiloride and Pregnancy: An Overview

Amiloride hydrochloride (Midamor®) is a pregnancy Category B medicine, meaning that it may be safe to use during pregnancy, although the full risks are not known.
 

Amiloride and Pregnancy Category B

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been studied in pregnant humans but that do not appear to cause harm to the fetus in animal studies.
 
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category B medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child. Generally, diuretics (including amiloride) should be used in pregnant women only when absolutely necessary. Amiloride is typically not used to treat high blood pressure during pregnancy.
 

Amiloride and Pregnancy: Final Thoughts

If you are pregnant or are thinking of becoming pregnant while taking amiloride, let your healthcare provider know. He or she will consider the benefits and risks of taking amiloride during pregnancy before making a recommendation in your particular situation.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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