Congestive Heart Failure Home > Amiloride-HCTZ Dosing

In many cases, the recommended starting dose of amiloride-HCTZ is one tablet daily (equal to 5 mg of amiloride and 50 mg of hydrochlorothiazide), taken with food. Your healthcare provider may increase this dosage to two tablets a day, if necessary. It's important to follow your healthcare provider's amiloride-HCTZ dosing guidelines carefully to ensure a successful treatment process.

Amiloride-HCTZ Dosing: An Overview

The dose of amiloride-HCTZ (Moduretic®) that your healthcare provider recommends will vary, depending on a number of factors, including:
  • Other medical conditions you may have
  • Other medications you may be currently taking
  • How you respond to amiloride-HCTZ.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Amiloride-HCTZ Dosing for High Blood Pressure or Fluid Retention

The recommended starting dose for any use is one amiloride-HCTZ tablet (equal to 5 mg of amiloride and 50 mg of hydrochlorothiazide), taken with food. If needed, your healthcare provider may increase your dose up to two tablets taken once daily with food.

General Information on Dosing With Amiloride-HCTZ

Considerations for people taking amiloride-HCTZ include the following:
  • The medication comes in tablet form. It is usually taken by mouth once a day, although some people will not need to take it every day. They may take amiloride-HCTZ every other day or even less frequently.
  • Amiloride-HCTZ should be taken with food.
  • The medication should be taken at the same time each day to maintain an even level in your blood.
  • Because amiloride-HCTZ increases urination, it is best to take it in the morning (to avoid needing to get up to use the bathroom throughout the night), unless your healthcare provider instructs you otherwise.
  • For amiloride-HCTZ to work properly, it must be taken as prescribed. It will not work if you stop taking it.
If you are unsure about anything related to amiloride-HCTZ dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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