Congestive Heart Failure Home > Aldactone Dosage

The usual starting dose of Aldactone for the treatment of high blood pressure is 50 mg to 100 mg daily. For the treatment of water retention, the recommended starting dose is 100 mg daily. When used as a long-term treatment for hyperaldosteronism, dosing usually ranges from 100 mg to 400 mg daily. The recommendation for treating hypokalemia is 25 to 100 mg.

An Overview of Aldactone Dosages

The dose of Aldactone® (spironolactone) that your healthcare provider recommends will vary depending on a number of factors, including:
  • Other medical conditions you may have
  • Other medications you may be currently taking
  • How you respond to Aldactone.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Dosing With Aldactone for Hyperaldosteronism

Aldactone can be used to diagnose hyperaldosteronism. For this purpose, the usual dose is 400 mg once daily for three to four weeks (the "long test") or for four days (the "short test"). Your healthcare provider will monitor your blood pressure and potassium levels to test whether you have hyperaldosteronism (if you do, your blood pressure and potassium levels should improve).
After the diagnosis, Aldactone can be used short-term to control hyperaldosteronism until surgery can be performed to correct the problem. It can also be used long-term for people who cannot or will not have surgery. For these uses, the dose is usually Aldactone 100 mg to 400 mg once daily. Alternatively, the daily dose can be split up into smaller, more frequent doses throughout the day.

Aldactone Dosage for High Blood Pressure

The recommended starting Aldactone dose for high blood pressure (hypertension) is 50 mg to 100 mg daily. This can be taken all at once or split up into two smaller doses per day. Your healthcare provider may need to adjust your dose if side effects occur or if your blood pressure is not under control.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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