Metoprolol and Digoxin

Prior to taking digoxin (Lanoxin®), tell your healthcare provider if you are taking certain beta blockers, including metoprolol (Lopressor®, Toprol-XL®). Taking digoxin with this or other beta blockers can increase your risk for a very slow heart rate, known medically as bradycardia.
Certain other beta blockers, like carvedilol (Coreg®, Coreg CR®) may increase the levels of digoxin in the body, potentially increasing your risk for side effects.
To help avoid these and other potential drug interactions with digoxin, make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Digoxin Drug Interactions for more information on the interaction with metoprolol. This article provides a detailed list of other products that can negatively react with digoxin and describes the complications these interactions may cause.)
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