Digoxin Drug Interactions

Paricalcitol
Paricalcitol may increase the amount of calcium in your blood, which increases the risk for serious digoxin side effects. Your healthcare provider may choose to monitor your calcium and digoxin levels with simple blood tests if you take these medications together.
 
Propafenone
Taking digoxin with propafenone may increase the levels of digoxin in the blood, potentially increasing your risk for serious side effects. Your healthcare provider may choose to monitor your digoxin blood levels using a simple blood test, especially when you start or stop taking propafenone.
 
Quinidine
Quinidine increases the amount of digoxin in your bloodstream, increasing your risk for serious digoxin side effects. Your healthcare provider may choose to decrease your digoxin dose if you start taking quinidine, and monitor your digoxin levels with a blood test.
 
Quinine
Quinine may increase the level of digoxin in your blood, potentially increasing your risk for digoxin side effects. Your healthcare provider may choose to monitor your digoxin level using a simple blood test if you start taking quinine.
 
Reserpine
Taking reserpine with digoxin may increase your risk for developing an abnormal heartbeat (heart arrhythmia). Your healthcare provider may decide to monitor you more closely if you take these medications together.
 
Sitagliptin
Sitagliptin may increase the levels of digoxin in your blood. Talk to your healthcare provider about this potential interaction before taking these medications together.
 
Sodium Polystyrene Sulfonate
Combining digoxin with sodium polystyrene sulfonate may increase your risk for serious digoxin side effects. Talk to your healthcare provider about this potential interaction before taking these medications together.
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Digoxin Drug Information

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