Digoxin Drug Interactions

Neomycin
Taking neomycin with digoxin may result in low digoxin blood levels, potentially making it less effective. Your healthcare provider may choose to monitor your digoxin levels with a simple blood test when you start or stop taking neomycin.
 
Neuromuscular-Blocking Medications
Combining digoxin with a neuromuscular-blocking agent may increase your risk for developing an abnormal heartbeat (heart arrhythmia). Your healthcare provider will closely monitor your heart if you take digoxin and need a neuromuscular-blocking drug. Make sure all your healthcare providers know you are taking digoxin.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Combining NSAIDs and digoxin may cause an increase in digoxin blood levels, potentially increasing the risk for serious side effects. Talk to your healthcare provider before taking an NSAID with digoxin. Your healthcare provider may need to monitor your digoxin blood level.
 
P-Glycoprotein (Pgp) Inducers
P-glycoprotein is a protein found in the body. One of its roles is to help remove substances, such as medications, out of the tissues so they can be excreted through the urine or feces. Pgp helps remove digoxin from the body. Certain other medications (known as Pgp inducers) increase the activity of Pgp.
 
Taking digoxin with one of these Pgp inducers causes digoxin to be removed from the body too quickly, potentially making it less effective. Your healthcare provider may choose to monitor your digoxin levels more closely if you take it with a Pgp inducer.
 
P-Glycoprotein (Pgp) Inhibitors
P-glycoprotein is a protein found in the body. One of its roles is to help remove substances, such as medications, out of the tissues so they can be excreted through the urine or feces. Pgp helps remove digoxin from the body. Certain other medications (known as Pgp inhibitors) decrease the activity of Pgp.
 
Taking digoxin with one of these Pgp inhibitors causes digoxin to be removed from the body more slowly, potentially increasing the amount of digoxin in your body and increasing your risk for serious side effects. Your healthcare provider may choose to monitor your digoxin levels if you take it with a Pgp inhibitor.
Ouch! 6 Types of Pain You Might Experience When Getting a Stent

Digoxin Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.