Chlorothiazide

Chlorothiazide is a prescription medication that is licensed to treat high blood pressure and fluid retention. By increasing the amount of salt and water that the kidneys remove from the blood, the diuretic can lower blood pressure and help with water retention. The medicine comes in tablet and liquid form, and is generally taken once or twice daily. Side effects may include weakness, dizziness, and diarrhea.

Chlorothiazide Drug Information

What Is Chlorothiazide?

Chlorothiazide (Diuril^®) is a prescription medicine that is used for high blood pressure and fluid retention. It is part of a class of medicines known as diuretics.

Who Makes Chlorothiazide?

Brand-name chlorothiazide is made by Merck. Generic versions are made by various manufacturers.

What Is Chlorothiazide Used For?

Specific uses of the drug include the treatment of:

High blood pressure (hypertension)
Water retention (edema) due to several causes, including congestive heart failure, cirrhosis, kidney failure (renal failure), and certain medications.

(Click What Is Chlorothiazide Used For? for more information, including possible off-label uses.)

How Does It Work?

Chlorothiazide is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is passed out through urine.

By increasing the amount of water removed from the blood, chlorothiazide causes a decrease in blood volume. Because of this effect, the drug can lower blood pressure and can also help with water retention.

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