As with any medicine, there are possible side effects with chlorothiazide. However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it well.
When side effects do occur, in most cases they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
A few of the possible side effects of this medication include:
- Low blood pressure (hypotension)
- Diarrhea or constipation
- Nausea and vomiting
- Muscle spasm
- Impotence (see Chlorothiazide and Impotence)
- Low blood potassium levels (hypokalemia) or other electrolyte imbalances.
(Click Side Effects of Chlorothiazide to learn about specific side effects, including potentially serious side effects that you should report immediately to your healthcare provider.)
Chlorothiazide can potentially interact with a number of medicines.
(Click Drug Interactions With Chlorothiazide for more information.)
You should talk with your healthcare provider prior to taking this medication if you have:
- Liver disease, including cirrhosis
- Kidney disease or kidney failure
- Systemic lupus erythematosus (lupus or SLE)
- Fluid or electrolyte problems, especially problems with high calcium levels (hypercalcemia)
- Any allergies, including allergies to sulfa drugs, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or trying to become pregnant (see Chlorothiazide and Pregnancy)
- Breastfeeding (see Chlorothiazide and Breastfeeding).
Tell your healthcare provider about all other medicines you are currently taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Chlorothiazide for more information on this topic, including information on who should not take the drug.)