Drug Interactions With Carvedilol
Certain Diabetes Medications
Carvedilol could increase the risk of dangerously low blood sugar (hypoglycemia) that can occur with some diabetes medications. In addition, carvedilol can mask some of the symptoms of low blood sugar (such as a rapid heart rate), making it less noticeable. This can lead to a dangerous situation. You may need to monitor your blood sugar more closely, especially when starting or stopping carvedilol, or even when changing your dosage.
If you are taking carvedilol and cimetidine, your body may metabolize carvedilol differently than intended. This can cause an increased level of carvedilol in your body. If you are using these medicines together, your healthcare provider may choose to monitor you more closely and/or adjust your carvedilol dose if needed.
If you take both clonidine and carvedilol, stopping clonidine without stopping carvedilol could increase the risk of dangerously high blood pressure, strokes, and other serious problems. You should stop taking carvedilol several days before you gradually reduce the dose of clonidine. Do not attempt this without the approval and supervision of your healthcare provider. If you are switching from clonidine to carvedilol, you should wait several days after stopping clonidine before starting carvedilol.
Carvedilol may increase the level of cyclosporine in your blood. Your healthcare provider should monitor your cyclosporine levels and adjust your cyclosporine dosage as necessary.
Combining carvedilol with digoxin may cause a dangerously slow heart rate (bradycardia). In addition, carvedilol may increase the level of digoxin in the blood. You may need to be monitored closely if you take these medications together. In some cases, it is not recommended to combine carvedilol with digoxin.