Drug Interactions With Captopril

Lithium
Captopril may increase the risk of lithium toxicity and may increase the lithium levels in the blood. Your healthcare provider may choose to monitor your blood lithium levels more frequently and may need to adjust your lithium dosage.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Captopril can interact with NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and captopril together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
  
Potassium
If you are taking a potassium product together with captopril, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and captopril together.
 
Potassium-Sparing Diuretics
If you are taking captopril and a potassium-sparing diuretic, your blood pressure may decrease too much and/or the levels of potassium in your blood may become too high. Your healthcare provider may choose to monitor your progress closely.
 

Final Thoughts

It is possible that not all captopril drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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