Nonsteroidal Anti-Inflammatory Drugs
If you have kidney disease or kidney failure, taking both
NSAIDs (including aspirin) and
captopril may add to the damage that your kidneys are already suffering. Also, NSAIDs may decrease the
blood pressure-lowering effects of captopril. Talk to your healthcare provider about using NSAIDs and captopril together.
Potassium Supplements
If you are taking a potassium supplement with captopril, the levels of potassium in your blood may become too high. This can cause serious problems. Talk to your healthcare provider about using potassium and captopril together.
Potassium-Sparing Diuretics
If you are taking both captopril and a potassium-sparing diuretic, your body may metabolize them differently than intended and/or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress closely if this is the case.
Lithium
If you are taking both captopril and
lithium, your body may metabolize the drugs differently than intended and increase the levels of lithium in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently if this is the case.
Nitrates
Using nitrates, such as nitroglycerin, and captopril together may cause a significant decrease in blood pressure. This could cause symptoms such as:
- A spinning sensation (vertigo)
- Lightheadedness
- Dizziness
- Fainting.
Talk to your healthcare provider before using nitrates and captopril together. He or she is in the best position to give you a recommendation for your particular situation.
Allopurinol
For people with kidney failure, taking
allopurinol and captopril together may increase the risk for infections. Talk to your healthcare provider about using allopurinol and captopril together. He or she may choose to monitor you more closely. Also, if you develop an infection, such as a fever or sore throat, let your healthcare provider know.
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