For people taking captopril, a cough is a possible side effect (it is a common side effect with all ACE inhibitors). Keep in mind that your healthcare provider cannot know beforehand whether you will have a side effect with a medicine that you have never taken. Therefore, if you notice a cough while taking captopril, talk to your healthcare provider. If the cough continues, he or she may recommend switching to another ACE inhibitor or to another heart failure or blood pressure medicine altogether.