Drug Interactions With Bumetanide

When certain medications are taken together, there is a chance of developing potentially negative drug interactions. With bumetanide, an interaction can occur if the drug is taken with certain antibiotics, blood pressure medications, and NSAIDs, for example. Some of these drug interactions with bumetanide can lead to extremely low blood pressure, hearing loss, or an electrolyte imbalance, among other things.

Drug Interactions With Bumetanide: An Introduction

Bumetanide (Bumex®) can potentially interact with a number of other medicines. Some of these drug interactions with bumetanide include:
 
  • Aminoglycoside antibiotics, such as:
o Amikacin (Amikin®)
o Gentamicin
o Kanamycin (Kantrex®)
o Neomycin (Neo-Fradin®)
o Streptomycin
o Tobramycin
 
  • Corticosteroids, such as:
o Hydrocortisone (Cortef®)
o Dexamethasone (Decadron®, Dexone®, Hexadrol®) 
  • Digoxin (Digitek®, Lanoxin®)
 
 
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
o Ibuprofen (Motrin®, Advil®)
o Indomethacin (Indocin®, Indocin SR®)
  • Probenecid (Benemid®, ColBenemid®)
 
  • Salicylates, such as:
o Aspirin (Ecotrin®, Bayer®, Anacin®)
o Choline magnesium trisalicylate (Trilisate®)
o Salsalate (Salflex®, Disalcid®, Amigesic®). 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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