Amiloride Overdose

While the symptoms vary from person to person, an amiloride overdose typically results in symptoms such as weakness, fever, and loss of consciousness. Treatment options for an overdose will depend on how recently the overdose occurred and if it was combined with alcohol or other medications. For a recent amiloride overdose, treatment may involve "pumping the stomach" and giving medications to counteract the overdose effects.

 

Amiloride Overdose: An Introduction

Amiloride hydrochloride (Midamor®) is a medication used for controlling high blood pressure and treating water retention (edema). The effects of an amiloride overdose will vary, depending on a number of factors, including how much amiloride was taken and whether it was taken with any other medicines, alcohol, and/or drugs.
 
If you happen to overdose on amiloride, seek immediate medical attention.
 

Symptoms of an Amiloride Overdose

It is not fully known what effects an amiloride overdose may cause in humans. Based on the effects of overdoses in animals and based on the way amiloride works, overdose symptoms may include:
 
  • Increased urination
  • Nausea or vomiting
  • Weakness
  • Fever
  • Flushed face
  • Low blood pressure
  • High potassium levels or other electrolyte imbalances.
     
This may cause signs or symptoms that include:
 
  • Lightheadedness, dizziness, or fainting
  • Decrease in urine output
  • Drowsiness, headache, or back pain
  • Slow or irregular heartbeat
  • Dry mouth
  • Increased thirst
  • Weakness
  • Tiredness
  • Restlessness
  • Seizures
  • Confusion
  • Muscle pain or cramps
  • Nausea or vomiting
  • Loss of consciousness.
     
(Amiloride Overdose Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;