Aldactazide and Impotence

Several side effects have been reported with Aldactazide, and impotence is one of them. Specifically, impotence appears to be caused by spironolactone (one of the components of the medication). If you are taking Aldactazide and impotence occurs, talk to your healthcare provider so that he or she can recommend an erectile dysfunction medication, adjust your Aldactazide dosage, or prescribe another diuretic.

Aldactazide and Impotence: An Overview

Aldactazide® (spironolactone-HCTZ) may cause impotence, as is common with many blood pressure medications. In clinical studies, impotence was one of the reported side effects of spironolactone (one of the components of Aldactazide), although the exact percentage of people who developed impotence was not reported.

What Is Impotence?

Impotence is usually defined as a total inability to achieve an erection, an inconsistent ability to do so, or a tendency to sustain only brief erections. Ultimately, impotence is the repeated inability to get or keep an erection that is firm enough for sexual intercourse. Impotence is also known as erectile dysfunction (or ED for short).
Spironolactone works as an aldosterone antagonist, which means that it blocks aldosterone. This is a hormone that causes fluid retention. Spironolactone also has some effect on testosterone and other androgen hormones. It may decrease the level of androgens (male hormones) or may block androgen receptors. It is likely that impotence caused by Aldactazide is due to the effects of spironolactone on male hormones.

Aldactazide and Impotence: Final Thoughts

It is impossible for your healthcare provider to know whether you will develop impotence while taking Aldactazide. It may also be difficult to determine whether impotence is caused by the medication itself or other problems.
If you are taking Aldactazide and impotence becomes a problem, make sure to talk with your healthcare provider. He or she may be able to recommend treatment options. Depending on how severe your symptoms are, your healthcare provider may also recommend that you take an erectile dysfunction medicine, adjust your Aldactazide dosage, or try another diuretic or blood pressure medication.
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